Education
As we fly through the universe of crazy these days, we are ignoring the biggest elephant (figuratively and literally) in the room, causing the most harm in this country: obesity. In America, it will not be a murky virus, economic ruin, or even terrorism that does us in--it appears it will be our inability to put down a fork and knife. Our waistlines are exploding, we are on numerous pharmaceutical drugs, yet we ignore the easiest solution to our weight gain woes: regular exercise and eating healthy. But what does that really mean? We will dig into the numbers, and I will warn you they are not pretty. To say we are fat as a nation is putting it nicely. The facts tell a very disturbing problem in our society, and it is getting worse at an alarming rate. Today I bring on my favorite scientist and data analyst to help me go through the numbers--Madame X. Yes, she has to use an alias, well, because people are crazy. Topics Discussed: * What the do the statistics really say about obesity * What is the “Healthcare Industrial Complex” * Why there is no money in healthy people * Why being fat is not beautiful and definitely not healthy * Why optimal health is the key to not getting Covid, not getting vaccinated * Is it possible some of us are genetically skewed to be overweight, or obese * Can you beat bad genetics and still live a life of optimal health and wellness * Why it is easy to maintain a healthy weight and lifestyle if you just pay attention * Why health fads are fads for a reason * Why your poor health negatively impacts everyone around you Episode Resources: * Link to Gary’s World Famous Health Book: https://www.thesimplelifenow.com/product/the-simple-life-guide-to-optimal-health-softcover/ * The Simple Life Website: https://www.thesimplelifenow.com *Make sure to signup and be a member of The Simple Life Insider's Circle at: https://www.thesimplelifenow.com/the-simple-life/ Show Links: https://www.hsph.harvard.edu/obesity-prevention-source/prevalence-incidence/ Divino et al , J Manag Care Spec Pharm_2021 Feb;27(2):210-222. Qian at el J Med Econ 2015;18(12):1020___ Prevalence and healthcare costs of obesity related comorbidities: evidence form an electronic medical records system in the United States Ravelli GP, Stein ZA, Susser MW. Obesity in young men after famine exposure in utero and early infancy. N Engl J Med 1976; 295: 349–353. Huang C, Li Z, Wang M, Martorell R. Early life exposure to the 1959-1961 Chinese famine has long-term health consequences. J Nutr 2010; 140: 1874–1878. age’ > 85th percentile vs infants in WFA < 85th percentile Parrillo L et al International Journal of Molecular Sciences 19 June 2019 Nutritional Factors, DNA Methylation and risk of Type2 diabetes and Obesity- Perspectives and Challenges Newborns of obese parents have altered DNA methylation patterns at imprinted genes Soubry et al, International Journal of Obesity (2015) 39, 650-657 Insulin like growth factor (IGF2) and H19 methylation at birth and risk of overweight and obesity in children. Perkins, E. et al J Pediatrics Jul 16(1)31-39 Valleso,L,et,al_IntJObes(2011)Dec;35(12)_Altered Hypothalamic Function in Diet-Induced Obesity Review of animal studies Alexander,J_JClinInvest(2017);127(1)24-32, Hypothalamic Inflammation in obesity and metabolic disease remarkable how rapidly overconsumption of a fat-rich diet results in acute changes in the feedback to metabolic endocrine signals (such as leptin and insulin signaling) and in hypothalamic inflammatory responses Obri et al_Cell Stress | JULY 2019 | Vol. 3 No. 7_Role of Epigenetics in hypothalamic energy balance control: implications for obesity Thomas K., et al, NatureResearch (2019)9:17373 Fotuhi et al Practical Neurology July 2013 Kim J et al, International J of Obesity 44, 1197 (2020)