Reversal of DOACs: Making critical advancements

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Lab Medicine Rounds

Miscellaneous


Timestamps:00:00 Intro00:43 Why is it important for physicians to understand about the reversal of these direct oral anticoagulants?03:09 The complications or the bleed rate was a lot less, with these direct oral anticoagulants?03:57 Although there is less severe bleeding, there was a concern by patients and physicians about, if it is severe, what is the plan? 04:51 What have we learned new? Are we learning more about what patient population to use them in, as well as the plans to reverse them?06:10 Can you elaborate a little bit about the idea for weekly monitoring for INR, why is it a big deal? 7:44 Could you give us an example of where it wouldn’t be ideal to do home INR monitoring for a given patient?09:06 Are there updates to what the reversal plans are, and how have they changed recently?12:34 Are there still some challenges that remain for reversing these direct oral anticoagulants?19:54 What do you think the future looks like for anticoagulant reversal? 23:47 OutroResources:https://pubmed.ncbi.nlm.nih.gov/30916798/