In the United States, privacy is considered a fundamental right. Yet today our activities are followed to a degree unfathomable not long ago by way of cell phones, online behaviors, and more. As genomic technologies continue to expand, another avenue now exists by which we may potentially be scrutinized: DNA sequence. Our genetic information contains our most private details, but we leave it everywhere and share the sequence closely with dozens or even hundreds of relatives. Laura Rivard, PhD, professor of biology at the University of San Diego, discusses ways in which our DNA may "escape" from our control, what can actually be done with the sequence, and whether there is cause for concern. Series: "Exploring Ethics" [Show ID: 34998]

Genetics (Video)

Your Genetic Privacy in the Big Data Era - Exploring Ethics

What defines consciousness? Can it develop in a petri dish? Patricia Churchland reviews the current state of brain organoid research and shares her views on how conciseness and physical structures within the brain intersect. She also cautions the media on the tendency to "over hype" new research advances. Series: "Stem Cell Channel" [Show ID: 35247]

Sensory Implications of Brain Organoids with Patricia Churchland

The study of brain organoids is leading to a better understanding of human development and potential therapies for neurological disorders. Yet when people hear the phrase "brain in a dish" it instantly brings to mind the stuff of science fiction - labs full of sentient brains thinking and plotting. Alysson Muotri explains why these organoids should not called "brains in a dish" and how they are being used to explain human processes previously inaccessible to study. While underscoring scientific value of these organoids, he also raises the question of what ethical questions demand an answer as the technology improves. Series: "Stem Cell Channel" [Show ID: 35245]

The Current Status of Human Brain Organoids Research with Alysson Muotri and Larry Goldstein

There are only two Northern White Rhinos left on the planet. How can we reverse extinction to save them and use the lessons learned to help other endangered species? Marisa L. Korody, PhD of the San Diego Zoo Institute for Conservation Research shares how scientists are using the latest in stem cell technology for a genetic rescue. Series: "Women in Science" [Show ID: 35227]

Stem Cells to the Rescue: Saving the Northern White Rhino from Extinction

Jennifer Doudna, co-discoverer of CRISPR-Cas9, discusses how genome editing with CRISPR technology is transforming biology. CRISPR-Cas9, an RNA-guided enzyme with remarkable abilities to recognize and cleave DNA, operates by mechanisms that both explain its biological function and provide insights into technology development. Doudna covers research into this amazing family of proteins: where they came from, how they work and how CAS-9-based technologies are revolutionizing research, biomedicine and agriculture. Series: "Frontiers of Knowledge" [Show ID: 35215]

Editing the Code of Life: Into the Future with CRISPR Technology with Jennifer Doudna - 2019 Nierenberg Prize for Science in the Public Interest

Marius Wernig, MD, PhD, discusses how his lab has worked to convert non-neuronal cell types (lymphocytes, pluripotent stem cells, fibroblasts, hepatocytes, lymphocytes) to neurons. The lab is now working on identifying the molecular mechanisms underlying induced lineage fate changes, the phenotypic consequences of disease-causing mutations in human neurons and other neural lineages. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Professional Medical Education] [Show ID: 35063]

How to Make a Neuron and How Pioneer Factors May Find Their Targets

Usted tiene la opción de someterse a exámenes para detectar una serie de trastornos genéticos en el embarazo. ¿Cómo se ejecutan estos tests y qué es lo que puede descubrirse? La Dra. Julia Cormano explica la diferencia entre exámenes de detección y pruebas de diagnóstico, qué se puede saber a partir de un examen de sangre, así como también qué esperar de la toma de muestras de vellosidades coriónicas y la amniocentesis. Series: "La Maternidad" [Spanish Language] [Show ID: 35087]

Pruebas Genéticas Durante El Embarazo

Scientists, including from UC Davis, have successfully sequenced the coast redwood and giant sequoia genomes, completing the first major milestone of a five-year project to develop the tools necessary to study these forests’ genomic diversity. Over the past 150 years, 95 percent of the ancient coast redwood range and about one-third of the giant sequoia range have been logged. If diversity has declined, it could leave the redwoods vulnerable to drought, fire and other stressors related to climate change. Series: "UCTV Prime" [Show ID: 35170]

Coast Redwood and Giant Sequoia Mega-Genomes Sequenced May Help Fight Effects of Climate Change

Scott Kelly spent a year in the International Space Station while his identical twin Mark Kelly was on earth. UC San Diego and many institutions studied the mental, cardiovascular, immune, genetic, muscular, microbial, bone, and eye changes in both twins to see the effects of long-term space travel. Changes were troubling, so NASA plans several more long-term space flights that will focus on genetic changes, bone loss, loss of vision, brain swelling, and Nutrition. Michael G. Ziegler, MD, is Professor of Medicine Emeritus at UCSD. He has studied astronaut health since 1978. He chaired NASA’s yearly cardiovascular reviews, helped devise current astronaut protocols, and studied physiologic and genomic changes during the Year in Space study.   Series: "Osher UC San Diego Distinguished Lecture Series" [Health and Medicine] [Science] [Show ID: 35085]

How a Year in Space Affects the Human Body with Dr. Michael G. Ziegler -- Osher UC San Diego

A team of engineers at UC Berkeley and the Keck Graduate Institute (KGI) of The Claremont Colleges combined CRISPR with electronic transistors made from graphene to create a new hand-held device that can detect specific genetic mutations in a matter of minutes. The device, dubbed CRISPR-Chip, could be used to rapidly diagnose genetic diseases or to evaluate the accuracy of gene-editing techniques. The team used the device to identify genetic mutations in DNA samples from Duchenne muscular dystrophy patients. Series: "UC Berkeley News" [Show ID: 35130]

New CRISPR-Powered Device Detects Genetic Mutations in Minutes

This CARTA symposium focuses on the contributions of scientists and scholars of anthropogeny who live and work in Africa. Himla Soodyall, National Health Laboratory Service (Johannesburg); University of the Witwatersrand, explores the links between the historical and genetic narrative of populations in southern Africa. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 34986]

CARTA presents Anthropogeny: The Perspective from Africa - Himla Soodyall: So Where Do We Come From?

Ultrasounds are one of the many tools available to help you have a healthy pregnancy. They can be used to monitor fetal growth, estimate risks for genetic disorders, discover the gender of your baby, and much more. Dr. Julia Cormano discusses the different types of ultrasounds that may be done during your pregnancy and how this technology can provide a unique view of your baby's development. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 34773]

Ultrasounds During Pregnancy

You have the option to screen for a number of genetic disorders in pregnancy. How are these tests performed and what can be discovered? Dr. Julia Cormano explains the difference between screening and diagnostic testing, what can be learned from a blood test, as well what to expect from chorionic villus sampling and amniocentesis. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 33874]

Genetic Testing During Pregnancy

Tony Wynshaw-Boris, MD, PhD describes his lab's efforts to use mouse and IPSC models to find commonalities that give insight into the complex disorder of autism. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Education] [Professional Medical Education] [Show ID: 34977]

Mouse and Human Induced Pluripotent Stem Cell Models of Autism Associated with Early Brain Overgrowth

Genetic testing has become a routine part of pregnancy, but what do the results mean? Genetic counselors play a valuable role in interpreting your results and guiding you through the process of what to do with that information. Dr. Julia Cormano sits down with genetic counselors Christina Brock and Andrea Procko to find out how they support patients throughout pregnancy. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 34915]

Genetic Counseling for Pregnancy

University of California faculty present the latest findings in genetic research and discoveries.

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Genetics (Video)

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