Have you ever wondered what neglected regions of the genome do? In this episode we hear about the search for AT rich region binding proteins.Jack Suitor (@JackTSuitor) talks to Raphael Pantier (@R_Pantier) and Kashyap Chhatbar (@kashyapchhatbar) from the Bird lab at the University of Edinburgh about their work on the DNA binding protein Sall4. They discover that Sall4 binds to AT rich regions which affects large scale gene expressions and enables differentiation. Sall4 could help time cellular differentiation as part of embryonic development and is therefore implicated in developmental disease. By getting more insight into proteins that bind AT rich regions we could learn more about the cause of some diseases.Art by @donohoho, intro and editing by @_applechew

BioPOD

Cell differentiation: When DNA met Sall4

This is the second episode of the BioPOD series: Scotland&apos;s Biotech Stories.In this instalment, BioPodder Liz Gaberdiel interviews Professor Lynne Regan on how to design biologically useful proteins. Proteins with unusual properties can enable super-resolution imaging, spontaneously self-assemble into structures, or coat a surface with a particular protein layer!Introduction and editing by Apple ChewMedia by Liz Gaberdiel and Chris Donohoe

Scotland's BioTech Stories: Engineered proteins in action

Welcome to a new BioPOD series: Scotland&apos;s Biotech Stories. In this installment, BioPodder Liz Gaberdiel interviews Dr. Marcus Wilson on Cryogenic electron microscopy (CryoEM), a  technique that has undergone some serious upgrades since its initial development in the 1960s. Introduction by Neelakshi Varma & Editing by Sam Haynes Media by Hanna Peach and Chris Donohoe 

Scotland's BioTech Stories: CryoEM - the cutting edge of structural biology with Dr. Marcus Wilson

Dear listeners,Welcome back to another episode of BioPod! Today we walk you through to potential of cyanobacteria: turning tasty sunlight into a high-product value delight!Apple Chew interviews Anton Puzorjov  from The McCormick Lab at The University of Edinburgh on his project supported by ScotBio Art by Christian Donohoe , Editing by Apple, Media by  Hanna Peach

Water 'bout cyanobacteria?: Producing high value products using sunlight ft. Anton Puzorjov

In the fourth and final installment of BioPOD&apos;s #Vaccine15 miniseries, we have Liz Gaberdiel interviewing Professor Neil Babbott on how vaccines can block viral transmission. Edited by Ruby White, Media by Hanna Peach. 

Evergreen: How to block viral transmission ft. Prof. Neil Mabbott

Ever wondered how vaccines are made in smaller batch scales, then upscaled to a world market? Hint: it&apos;s not the same as cooking a larger lasagne when family comes to visit. Tune into our third installment of #Vaccine15 to learn about the large scale production of vaccines.In this episode, BioPodder Liz Gaberdiel interviews Dr Prerna Vohra. Editing by Hanna Peach.Enjoy, and #GetVaccinated! 

COVID19: How to mass produce a vaccine ft. Dr Prerna Vohra

In this episode of our four-part vaccine 15-minute miniseries, biopodder Chris Donohoe  interviews Dr. Thomas Williams on how to track and tackle the different COVID variants. edited by Apple Chew (Yen Peng) media and art by Hanna Peach

Viral Variants: How to track and tackle COVID variants ft. Dr Thomas Williams

Our #Vaccine15 four-part 15-minute miniseries begins today! This week is all about how COVID vaccines were developed and designed with @CTaitBurkard from @EdinburghUni @roslininstituteInterviewer and Art @donohohoEditing by @_applechewMedia and Art @hanna_peach_ 

Eureka! How To Design A Vaccine ft. Dr Christine Tait-Burkard

Explore the edges of known biology and meet the people working to figure it all out - a podcast direct from the PhD students at the heart of university research. BioPOD is the official podcast from the School of Biological Sciences at the University of Edinburgh.